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엠여성의원 생식의학연구실은 난임으로 고통 받는 부부들에게 희망과 잉태의 기쁨을 안겨드리고자 전문연구인력과 첨단 연구시설을 갖추고 있습니다.
개인의 특성과 원인이 종합적으로 고려되어야 하는 난임 치료는 오랜 경험과 높은 의학 기술이 필요한 만큼 의료진과의 소통을 통해 21세기 생식의학연구를 선도 하는 국내 최초, 세계 최고의 연구소를 지향합니다.
과배란유도 시험관아이 뿐만 아니라 정상 월경 주기를 갖고 있는 환자의 내분비학적 변화와 자연 배란에 대한 연구를 통해 자연배란주기 시험관아기 프로그램이 널리 보급될 수 있도록 최선을 다하고 있습니다.
여성불임과 남성불임의 난점을 극복하기 위해 자동화 정액검사, 세포질 내 정자 주입술, 레이저 보조부화술, 난자·정자·수정란의 동결보존, 착상 전 유전자 진단 등의 연구를 수행하고 있습니다.
개인의 특성에 따른 맞춤 시험관 아기 시술의 수행을 위하여 배아 파편 제거술 (배아성형술), 착상중진술을 도입하여 고객의 특성에 맞는 차별화된 시스템을 구축하고 있습니다.
유전학 분야에서는 산모 혈액으로 NGS(Next Generation Sequencing)방법을 이용한 태아 기형아 진단법을 Labgenomics와 공동연구를 시행하여 임상적용 가능성을 확인하고자 노력하고 있습니다.
난임으로 고통 받는 이들이 나의 가족이라는 생각으로 생명의 존엄성과 윤리성을 지키며 개인의 특성과 원인을 고려하여 양질의 배아를 생산하기 위해 끊임없이 연구하고 노력할 것을 약속드리며 임신을 기쁨으로 보답하겠습니다.
- - 건국대학교 축산학과 석사 졸업
- - 서울마리아병원 마리아기초의학연구소 (1996-1997)
- - 노원을지병원 의과학연구소 (1998-2002)
- - 제일병원 의학연구소 불임연구실 (2006-2012)
- - 대한 생식의학회 정회원
- 1. 국내외 논문
- Y-S Park, MK Kim, CK Lim, S-H Lee, D-W Park, JT Seo and KM Yang. Efficacy of cryopreservation of embryos generated by intracytoplasmic sperm injection with spermatozoa from frozen testicular tissue. J Assist Reprod Genet. 31:1331-1336. 2014
MR Shin, HW Choi, MK Kim, SH Lee and CK Lim. In vitro development and gene expression of frozen-thawed 8-cell stage mouse embryos following slow freezing or vitrification. Clinical and Experimental Reproductive Medicine. 38(4): 203-209, 2011.
YS Park, MK Kim, SH Lee, JW Cho, IO Song and JT Seo. Efficacy of testicular sperm chromatin condensation assay using aniline blue staining in the IVF-ET cycle. Clinical and Experimental Reproductive Medicine. 38(3): 124-127, 2011.
MK Kim, SH Lee, SJ Choi, HW Choi, DW Park, CK Lim, IO Song and HS Lee. Effect of cryopreservation of sibling 2PN zygotes on cumulative delivery rates in the human IVF-ET program. . Kor. J. Fertil. Steril. 37(4): 329-37. 2010.
MK Kim, SJ Choi, HW Choi, KH Bang, HO Kim, KM Yang, MK Koong, JY Jun and JH Jun. Pregnancy and implantation rates related to serum estradiol concentrations of controlled ovarian hyperstimulation in fresh IVF-ET and frozen-thawed ET. . Kor. J. Fertil. Steril. 34(3): 197-205, 2007.
HG Lee, MK Kim, DS Ko, HG Kang, DH Kim: Effect of xenoestrogenes on gene expression of cytochrome P450 genens in in vitro cultured mice spermatogenic cells. Kor. J. Fertil. Steril. 28(1): 1-16. 2000.
HG Lee, MK Kim, DS Ko, HG Kang, DH Kim: The expression of testis-specific genes in vitro cultured spermatogenic cells of pre-pubertal mice. Kor. J. Male Science. 18(1):33-40, 2000.
HG Kang, MK Kim, DH Kim, SW Han, DH Choi, HJ Lee and MK Kim: Effect of fertilization promoting peptide on kinematic parameters capacitation and acrosome reaction in human spermatozoa. Kor. J. Fertil. Steril. 27(2):201-209, 2000.
HG Kang, MK Kim, DH Kim, SW Han, DH Choi, JH Lee and MK Kim: Effect of fertilization promoting peptide on kinematic parameters capacitation and acrosome reaction in human spermatozoa. Kor. J. Fertil. Steril. 27(2):201-209, 2000.
HG Kang, DH Kim, SW Han, MK Kim, HC Kwon, HJ Lee and MK Kim: Effects of reactive oxygen species on motility in human spermatozoa. Kor. J. Fertil. Steril. 27(4):393-403, 2000.
HJ Lee, MK Kim, HG Kang, DH Kim, S Han and DS Ko: Effects of bisphenol and octylphenol on TM3 cell: Expression of cytochrome P450scc and estrogen receptor-alpha mRNA. Kor. Dev. Reprod. 4(2):215-220, 2000.
DH Kim, MS Lee, JG Kang, SW Han, MK Kim, WI Park, HT Lee, KS Chung and HJ Lee: Use of non-contact type diode laser on assisted hatching of mouse embryos. Kor. J. Fertil. Steril. 26(2):185-192, 1999.
MK Kim, EY Kim, BK Yi, SH Yoon, SP Park, KS Chung and JH Lim: In vitro/in vivo development of mouse oocytes vitrified by EFS. Kor. J. Fertil. Steril. 25(1):87-92, 1998.
MK Kim, EY Kim, BK Yi, SH Yoon, SP Park, KS Chung and JH Lim: In vitro/in vivo development after thawing of vitrified mouse blastocysts by culture condition and embryo transfer method. Kor. J. Anim. Reprod. 24(3):347-353, 1997.
EY Kim, MK Kim, BK Yi, HS Lee, SH Yoon, SP Park, KS Chung and JH Lim: In vivo development of mouse IVF/IVC embryo treated with epidermal growth factor (EGF). Kor. J. Anim. Reprod. 24(2): 261-265, 1997.
SJ Hum, NH Kim, EY Kim, MK Kim, SK Cha, SH Yoon, SP Park, KS Chung and JH Lim: In vitro developments of porcine embryos produced by in vitro fertilization and parthenogenetic activation. Kor. J. Anim. Reprod. 24(1): 43-49, 1997.
EY Kim, SJ Uhm, MK Kim, SH Yoon, SP Park, KS Chung and JH Lim: Study on epidermal growth factor (EGF) and expression of EGF-Receptor (EGF-F) in mouse IVF/IVC embryo. II. Expression of EGF-R on the inner cell mass (ICM) of mouse IVF/IVC blastocyst. Kor. J. Anim. Reprod. 24(1): 21-26, 1997.
EY Kim, SJ Uhm, MK Kim, SH Yoon, SP Park, KS Chung and JH Lim: Study on epidermal growth factor (EGF) and expression of EGF-Receptor (EGF-F) in mouse IVF/IVC embryo. I. Additive effect of EGF and expression of EGF-R on mouse IVF embryo development. Kor. J. Anim. Reprod. 24(1): 13-20, 1997.
EY Kim, SJ Uhm, MK Kim, SH Yoon, SP Park, KS Chung and JH Lim: Human Blastocysts : The correlation between embryo microscopical assessments and their cell number. Kor. J. Anim. Reprod. 23(3): 319-326., 1996.
MK Kim, CS Baik, SJ Jum, EY Kim, SH Yoon, SP Park, KS Chung and JH Lim: Sister chromatid exchange (SCE) frequency and in vitro development of mouse zygote cryopreserved by vitrification . Kor. J. Fertil. Steril. 23(3):379-384, 1996.
SJ Uhm, EY Kim, MK Kim, T Kim, SH Yoon, SP Park, KS Chung and JH Lim: Effect of epidermal growth factor on In vitro maturation in pig immature oocytes. Kor. J. Anim. Reprod. 23(3): 303-310, 1996.
CS Baik, MK Kim, SM Lee, SM, JH Kim, YK Baik, HT Lee, KS Chung: Study on the analysis of chromosome abnormality by flow cytometric and cytogenetic methods. Kor. J. Anim. Reprod. 23(1): 73-79, 1996.
MK Kim, HS Lee, JS Uhm, EY Kim, SH Yoon, SP Park, KS Chung and JH Lim: cryopreservation of mouse IVF zygotes by vitrification. Kor. J. Anim. Reprod. 20(2):119-126, 1996.
MK Kim, JH Kim, SM Lee, HS Chung-Ha, HT Lee and KS Chung: In vitro culture following purification mouse spermatogenic cells. Kor. J. Anim. Reprod. 20(1):43-52, 1996.
SM Lee, CS Baik, DB Koo, MK Kim, JH Kim, HD Park, HT Lee and KS Chung: Fertiization by microinjection of mouse round spermatid. Kor. J. Anim. Reprod. 19(3):171-179, 1995. - 2. 국내외 학술발표
- MK Kim, SH Lee, IO Song, JT Seo and YS Park. Pregnancy and delivery rates of frozen-thawed embryos fertilized with sperm obtained from fresh- or frozen-thawed testicular. The 66th annual meeting of American Society for Reproductive Medicine, Denver, Colorado, 2010.
MR Shin, HW Choi, SH Lee, MK Kim, IO Song and CK Lim. Development and gene expression of thawed 8-cell stage mouse embryos following slow freezing or vitrification. ESHRE 25th annual meeting, 2009 (Oral presentation)
MK Kim, HJ Kang, DW Park, SB Hong, MR Shin, IS Kang, JY Kim and CK Lim. Comparison of cumulative pregnancy rates in IVF-ET cycles between culture of all fertilized eggs and split zygotes after freezing at sibling pronuclear stages in the patients having small number of zygotes. 15th world congress on in vitro fertilization, Geneva, Switzerland, 2009.
HW Choi, HJ Kang, MR shin, MK Kim, SH Lee, MK Koong, IO song and CK Lim. Developmental potential on day 3 fast-cleaving embryos and pregnancy outcome of fast-cleaving embryos transfer. 15th world congress on in vitro fertilization, Geneva, Switzerland, 2009.
SH Lee, DW park, MK Kim, MR Shin, IO Song and CK Lim Triploid zygote formation rate and ART outcomes. The 65th annual meeting of American Society for Reproductive Medicine, Atlanta, 2009
DW Park, MK Kim, CW Park, JW Lee, HJ Lim, HG Kang and CK Lim. 완만동결법(Slow freezing method)과 유리화 동결법 (vitrification)을 이용한 소 난소조직의 동결보관 방법의 비교연구. 춘계대한생식의학회, 2008.
MK Kim, D-W Park, SH Lee, KH Bang, IO Song, IS Kang, CK Lim. Comparison of cumulative pregnancy rates in between culture of all fertilized eggs and split zygotes after freezing at sibling 2PN stages to transfer on day 3. 추계대한생식의학회, 2008.
최수진, 김묘경, 이선희, 최혜원, 방경희, 송인옥, 궁미경, 강인수, 전진현. 여성 환자 나이에 따른 신선 배아이식과 동결-융해 배아이식의 임상적 효용성 비교. 대한생식의학회 제52차 춘계학술대회. 2007.
S Han, MK Kim, DH Kim, HG Kang, WI Park, HC Kwon: The relation of the maturity of retrieved oocytes and developmental velocity of embryos with pregnancy rates in IVF-ET program (P-225_. The 56th annual meeting of American Society for Reproductive Medicine, San Diego, 2000.
DH Kim, HG Kang, S Han, MK Kim, HT Lee, GS Chung, HJ Lee : Developmental capacity of mouse oocytes derived from in vitro and in vivo grown preantral follicles. Theriogenology 53:456. Abst, 2000.
HG Kang, MK Kim, DH Kim, S Han, HJ Lee and MK Kim: Effects of fertilization promoting peptide on kinematic parameters, capacitation and acrosome reaction in human spermatozoa (P-132). The 33rd annual meeting of the Society for the Study of Reproduction. Madison, 2000.
HJ Lee, MK Kim, DS Ko, SW Han, DH Kim, HG Kang : Effects of BPA and OP on protamine-2 and P450 family gene expression of spermatogenesis in mice (A-366). The 49th annual meeting of the American Society of Human Genevtics. 1999.
MK Kim, DS Ko, HG Kang, DH Kim, SW Han, SY Hong and HJ Lee : In vitro culture of spermatogenic cells and gene expression in pre-pubertal mouse (P-164). 11th world congress on in vitro fertilization & human reproductive genetics, Sydney, 1999.
HG Kang, MK Kim, DH Kim, SW Han, DY Choi, TK Yoo, HJ Lee, MK Kim : Effects of reactive oxygen species on acrosome reaction, lipid peroxidation and fertilization in mouse spermatozoa (P-52). 11th world congress on in vitro fertilization & human reproductive genetics, Sydney, 1999.
Lee SM, MK Kim, DB Koo, JH Kim, HT Lee and KS Chung: In vitro fertilization of mouse oocytes by fusion with round spermatids. Theriogenology. 1996.
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